Problematic alcohol use (70.1 for existing, 70.0 for former, and 76.0 for never ever problematic alcohol use, p=.039), and depressive symptoms (77.6 for lowest, 70.two for middle, and 68.1 for highest tertile, p.001) (Table two). In multivariable analysis, education, former problematic alcohol use, and depressive symptoms remained independently associated with patient activation. For each one-point raise in CESD depression score, the PAM score decreased by a half a point in adjusted evaluation (= -0.52, 95 self-assurance interval (CI) -0.77?.27 for CESD score as continuous variable). Of 333 patients prescribed antiretrovirals, 262 (78.9 ) had a CD4 count200 cells/mL3, 223 (67.2 )RESULTSOf 55 eligible providers, 45 (81.8 ) agreed to participate. Two providers declined. The remainder of providers who weren’t enrolled were not pursued due to the fact we reached enrollment targets. Providers had a imply patient panel size of 123 patients, and we enrolled a imply of ten individuals per provider. We identified 617 eligible patients. Providers refused to let 18 patients to become approached for the study, since the provider felt also rushed (n=12), or that the patient may well be as well sick (n=5), or the patient was only returning for labs as an alternative to a total check out (n=1). Of the remaining 599 patients approached, 434 agreed to participate and completed all study procedures. Of 165 individuals who declined to enroll inside the study, the most frequent motives were that they did not have time for you to comprehensive the interview (n=106), that they weren’t feeling nicely (n=22), and that they weren’t considering investigation studies (n=13). A single participant who did not comprehensive the PAM wasTable 1. Patient Characteristics (n=433) Mean age in years (SD) Race, n ( ) White African American Latino Other Male gender, n ( ) Higher school degree, n ( ) Imply social status (SD) Problematic alcohol use, n ( ) Existing Former Under no circumstances Illicit drug use, n ( ) Existing Former Never ever Mean CESD Score (SD) With provider5 years, n ( ) Prescribed antiretrovirals, n ( ) 45.four (9.5) 105 254 62 12 285 313 4.2417920-98-8 custom synthesis 50 (24.1175052-07-9 Price 3) (58.PMID:22943596 7) (14.three) (two.8) (66.0) (72.3) (two.0)39 (9.2) 209 (49.three) 176 (41.five) 121 206 103 ten.9 144 333 (28.1) (47.9) (24.0) (6.four) (33.4) (78.5)CESD Center for Epidemiological Studies Depression scaleJGIMMarshall et al.: Patient Activation and HIV OutcomesTable two. Univariate and Multivariable Associations with Patient Activation (n=433) Mean PAM Score (SD) Age tertile (years) 18?two 43?9 50 Race: White African American Latino Other Gender Female Male Higher college degree No Yes Social status tertile Lowest Middle Highest Problematic alcohol use In no way Former Current Illicit drug use By no means Former Existing Depression tertile Lowest Middle Highest Time with provider 5 years five years Prescribed antiretrovirals No Yesp -value*Multivariable coefficient (95 CI) ?Table three. Associations Involving Patient Activation and HIV Clinical Outcomes Amongst Individuals Prescribed Antiretroviral Therapy* (n=411) CD4200 cells/mL3 Adherence Viral Viral suppression suppression Model A aOR (95 CI) aOR (95 CI) aOR (95 CI) Model B aOR (95 CI)0.894 72.five (16.three) 72.0 (17.0) 72.four (16.four) 0.539 71.8 73.5 70.0 64.7 (15.four) (16.six) (18.0) (13.three) 0.294 73.eight (15.eight) 71.six (16.five) 0.001 68.0 (15.9) 74.0 (16.5) 0.039 70.3 (15.eight) 74.three (17.1) 74.5 (16.9) 0.002 76.0 (15.7) 70.0 (16.6) 70.1 (17.eight) 0.151 75.1 (15.9) 72.4 (16.8) 70.1 (16.3) 0.001 77.six (16.9) 70.two (15.7) 68.1 (15.1) 0.322 72.7 (16.five) 71.eight (16.5) 0.107 69.9 (15.4) 72.9 (16.8)Ref 2.53 (-1.25, six.31) four.0.